Iran's Foreign Minister Mohammad Javad Zarif has dismissed US President Donald Trump's "genocidal taunts" and warned him not to threaten the country.
With tensions rising, Mr. Trump tweeted on Sunday: "If Iran wants to fight, that will be the official end of Iran." Zarif said the president should look at history.
"Iranians have stood tall for millennia while aggressors all gone... Try respect - it works!"
The US has deployed additional warships and planes to the Gulf in recent days. But Trump's tweet marked a shift in tone after recent attempts by him to downplay the possibility of a military conflict with Iran.
When asked by reporters on Thursday if the US was going to war, he said: "I hope not." His warning to Iran on Sunday was issued hours after a rocket was fired into the heavily fortified Green Zone in the Iraqi capital, Baghdad, and hit a building about 0.5km (0.3 miles) from the US embassy.
The US recently evacuated non-emergency staff from the mission because of what it called a "serious" threat reportedly linked to Iran-backed forces in Iraq.
Writing on Twitter on Monday, Iran's foreign minister said the US president was being "goaded" by what he called the "B Team" - a reference to US National Security Adviser John Bolton, Israeli Prime Minister Benjamin Netanyahu, and Saudi Crown Prince Mohammad bin Salman.
Tensions began rising earlier this month when the US ended exemptions from sanctions for countries still buying from Iran.
The decision was intended to bring Iran's oil exports to zero, denying the government its main source of revenue.
Trump reinstated the sanctions last year after abandoning a landmark 2015 nuclear deal between Iran and world powers that he wants to renegotiate.
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